Opioid-induced hyperalgesia (OIH)

• Opioid-induced hyperalgesia (OIH) is defined as a state of nociceptive sensitization caused by exposure to opioids.

• The condition is characterized by a paradoxical response whereby a patient receiving opioids for the treatment of pain could actually become more sensitive to certain painful stimuli.

• โดนตัวแล้วเจ็บปวดมาก , 

• Myoclonus is an uncontrollable twitching and jerking of various muscle groups, most frequently of the extremities

Treatment

หยุด MO 

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