Opioid-induced hyperalgesia (OIH)
Opioid-induced hyperalgesia (OIH) is defined as a state of nociceptive sensitization caused by exposure to opioids.
The condition is characterized by a paradoxical response whereby a patient receiving opioids for the treatment of pain could actually become more sensitive to certain painful stimuli.
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Myoclonus is an uncontrollable twitching and jerking of various muscle groups, most frequently of the extremities
Treatment
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